When assessing skin cancer specimens, the pathologist must address three main questions: what is the lesion; what prognostic information can be inferred; and is the lesion completely excised? In many instances, the assessment of the margins is the most important part of the pathological examination, since most skin cancers can be cured by complete excision.
It is salutary to note that ‘recurrent’ skin cancers are very often the result of recrudescence of a lesion that was incorrectly reported as having been completely excised.
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