Ibuprofen liver impact could be severe

Liver damage has generally been thought of as a rare side effect of taking ibuprofen, a common pain medication available over the counter in many countries. New research is now indicating that the effects of ibuprofen on the liver may be more common and extensive than previously suspected.

Conducted by researchers at the University of California, a recent mouse study investigated the effects of moderate ibuprofen dosage on the liver. Using advanced mass spectrometry, the researchers determined that ibuprofen caused many more protein expression changes in the liver than expected. What was even more surprising is that the changes differed depending on the sex of the mice.

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