John Worthington

John Worthington

Senior Lecturer in Infection Biology, Lancaster University
The intestinal epithelium offers the first interaction between commensal bacteria, pathogens and our bodies’ largest immune system. Inappropriate immune responses drive inflammatory bowel disease (IBD) or excessive inflammation during infection. My research focuses on the epithelial enteroendocrine cells (EECs), which release peptide hormones in response to nutrients allowing their efficient digestion. EEC alterations are strongly associated with inflammation, yet the possibility of interactions between our gut’s endocrine and immune systems remains overlooked. Understanding the mechanistic cross-talk between enteroendocrine and immune cells will identify the immunoendocrine axis as a key feature of intestinal health which could be therapeutically targeted during disease.

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POTS – What You Need to Know

Tuesday 17th February, 7pm - 9pm AEDT

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Cardiac Electrophysiologist; The Royal Adelaide Hospital; Clinical Professor, The University of Adelaide

Hear the latest evidence-based management options for POTS - a common, yet poorly recognised and misunderstood autonomic dysfunction condition in our community. Join Prof Dennis Lau for an update on POTS, who is at risk, presenting symptoms and how it can be diagnosed in the primary care setting.