In this Healthed lecture, Prof Crawford will provide a detailed practical understanding of the risk-benefit considerations as well as an update on AZ clots AND bleeds. In addition, A/Prof Crawford will provide an update on the Delta variant as well as information on the “Lambda Variant” and other variants of concern that may arrive in Australia soon and also cover which vaccines currently work against which variants.As we pivot toward the Pfizer vaccine, we may start to see cases of myocarditis. It’s important to recognise this very rare phenomenon as well as be able to explain it to your patients. The questions of vaccination in pregnancy continues to be an issue that concerns health professionals. A/Prof Crawford will describe the current available data concerning safety and effectiveness of the Covid vaccines in this scenario.