There is no debate – postpartum depression can be a devastating disease for a new mother.However, what is probably less well-recognised is the long-term consequences of that illness on the child.The latest findings from an ongoing longitudinal UK study of parents and infants shows that children whose mother was assessed as having moderate to severe depression at both two and eight months after delivery had a substantially increased risk of adverse outcomes across a number of child measures from behaviour and learning to mental health up to 18 years later.The observational study known as the British Avon Longitudinal Study of Parents and Children(ALSPAC) has followed over 9800 women who were pregnant in the early 1990s.In the latest findings, published in JAMA psychiatry, the researchers noted that women who still had moderate to severe depression at eight months postpartum, were likely to still have depression 11 years later. And the children of these women had a four- fold increased risk of behaviour problems as a pre-schooler, twice the risk of being poor at maths in high school and a seven fold increased risk of depression as an adult.Conversely, if the postpartum depression was not persistent at either the moderate or severe level there appeared to be no increased risk of behaviour and learning problems or depression in the offspring, which is reassuring.The study findings published in JAMA psychiatry raise a number of interesting questions.“Having established a highly vulnerable group of mothers still does not answer the question of what to do about interventions, or who, when, or how to treat,” the author of an accompanying editorial says.The design of the study meant the researchers were unable to determine the effects of maternal treatment on reducing postpartum depression and improving child outcomes. As the editorial author also points out, there is also considerable debate whether treatment should focus mainly on the mother and her illness or be directed at the mother-infant relationship.Nonetheless, it is clear that, as a first step at least, these mothers with persistent severe depression need to be identified.Screening for depression which now focuses on pregnancy and the immediate postpartum period needs to be extended to a year after delivery.“Screening both early and late in the first postpartum year will enable the identification of women with persistent [postnatal depression] and thus the offer of appropriate treatment,” the study authors concluded.Ref:JAMA Psychiatry doi:10.1001/jamapsychiatry.2017.4363 doi:10.1001/jamapsychiatry.2017.4265
Expert/s: Dr Linda Calabresi