Men, mortality and the Y chromosome

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EA
0.5 hours

Educational Activities (EA)
These are activities that expand general practice knowledge, skills and attitudes, related to your scope of practice.

RP
0.5 hours

Reviewing Performance (RP)
These are activities that require reflection on feedback about your work.

MO
1 hours

Measuring Outcomes (MO)
These are activities that use your work data to ensure quality results.

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Description

In this episode, Geneticist Prof Jenny Graves joins host Dr David Lim to discuss the strange biology of the Y chromosome, its surprising links with men’s health, and why some men are more vulnerable to losing it as they age. Drawing on decades of work in sex chromosomes and evolution, she explores what Y chromosome loss might mean for risk assessment, lifestyle advice, and future screening:

  • Why the loss of the Y chromosome (LOY) is more common than other chromosomal changes
  • Links to age-related chronic diseases
  • How mosaicism for the Y chromosome develops with age
  • How future screening for LOY help risk stratify patients
  • A long-view perspective on the evolution and future of the human Y chromosome

 

Expert: Prof Jenny Graves, Evolutionary Geneticist

Host: Dr David Lim, GP & Medical Educator

Total time: 34 mins

 

Last Updated: 5 May, 2026

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