Resistant “essential” hypertension: Could it be primary aldosteronism?

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Educational Activities (EA)
These are activities that expand general practice knowledge, skills and attitudes, related to your scope of practice.

RP
0.5 hours

Reviewing Performance (RP)
These are activities that require reflection on feedback about your work.

MO
1 hours

Measuring Outcomes (MO)
These are activities that use your work data to ensure quality results.

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Description

In this episode, A/Prof Jun Yang and host Dr Charlotte Hespe discuss primary aldosteronism (PA) as a common yet under-recognised cause of hypertension, particularly in resistant cases. She provides practical, GP-focused guidance on who to screen, how to interpret aldosterone–renin testing, and how targeted treatment can reduce cardiovascular and renal risk:

  • Review how excess aldosterone drives hypertension and contributes to cardiovascular, renal and metabolic damage
  • Learn how to screen for PA using aldosterone, renin and the aldosterone–renin ratio
  • Recognise the pathways from abnormal screening to confirmatory testing, subtyping, and targeted treatment
  • Understand how earlier detection and treatment of PA can reduce major events such as stroke, heart failure and chronic kidney disease

 

Expert: A/Prof Jun Yang, Endocrinologist and Research Specialist

Host: Dr Charlotte Hespe, GP & Head of General Practice and Primary Care Research

Total time: 26 mins

 

Recommended resources:

 

Last Updated: 14 Apr, 2026

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A/Prof Jun Yang

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A/Prof Jun Yang

Research Scientist, Endocrine Hypertension Group at Hudson Institute; Consultant Endocrinologist, Monash Health; Senior Postdoctoral Fellow, Department of Medicine, School of Clinical Sciences at Monash Health

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