Articles / Clinical Conversations: Japanese Encephalitis – A Practical Approach for GPs | Part one


writer
Microbiologist and Infectious Diseases Physician; Senior Staff Specialist, The Department of Microbiology and Infectious Diseases, Royal North Shore Hospital
This is part one of a three part series. Read part 2
Practice points
• Japanese encephalitis is caused by a flavivirus, and the other flaviviruses that people will know extremely well are Dengue, Zika virus, yellow fever, West Nile virus and most are spread by mosquitoes.
• The hosts are primarily pigs and so the Culex or Aedes mosquitoes get infected and spread it to spread it to humans, horses and donkeys, all of which are dead-end hosts.
• The big problem really is that we can only define detection when a case of meningitis or encephalitis occurs and all the usual diagnostic tests are negative. Patients need to be referred as the diagnostic test is a lumbar puncture.
• The chance of getting sick once you get infected is extremely low, but if you do get symptoms, then there might be an acute febrile illness. If you get any neurological symptoms, unfortunately, the outcomes usually bad.
• More likely than not the disease is going to become endemic. However, there might be very few cases, and then there may be spikes every now and then.

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writer
Microbiologist and Infectious Diseases Physician; Senior Staff Specialist, The Department of Microbiology and Infectious Diseases, Royal North Shore Hospital


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