Coeliac disease testing

Coeliac disease testing

Coeliac disease is a common disorder affecting the gastrointestinal tract, secondary to an immunologic reaction to gluten. At present it can only be managed by lifelong avoidance of gluten, and thus presents a challenge for patients and their health care professionals.

Epidemiology

Coeliac disease was first characterised in the late 1940s with diarrhoea and failure to thrive in young children. The wartime shortage of wheat, and adoption of a gluten-free surrogate diet, allowed their symptoms to improve. When wheat was re-introduced into their diets their condition worsened again.

Initially thought to be a rare disease of children, we now recognise coeliac ...

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